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temsirolimus

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMTemsirolimus
CTRPv2temsirolimus
PharmacoGx temsirolimus

External IDs

DatabaseIdentifier
Smiles: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Inchikey: CBPNZQVSJQDFBE-FUXHJELOSA-N
Pubchem: 6918289

Annotated Targets

MTOR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to temsirolimus


Feature TypeStandardized
Nominal ANOVA
mRNA PSMB8 FIMM pan-cancer AAC -0.63 0.0002
mRNA CLMP GDSC1000 pan-cancer AAC 0.14 0.0002
mRNA NOS1 FIMM pan-cancer AAC 0.54 0.0002
mRNA SP140 GDSC1000 pan-cancer AAC 0.15 0.0002
mRNA XPC GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA NEXN GDSC1000 pan-cancer AAC 0.14 0.0002
mRNA AGAP1 GDSC1000 pan-cancer AAC -0.14 0.0002
mRNA VAMP1 GDSC1000 pan-cancer AAC 0.14 0.0002
mRNA SEPT2 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA MARC1 GDSC1000 pan-cancer AAC -0.14 0.0003
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