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temsirolimus

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMTemsirolimus
CTRPv2temsirolimus
PharmacoGx temsirolimus

External IDs

DatabaseIdentifier
Smiles: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Inchikey: CBPNZQVSJQDFBE-FUXHJELOSA-N
Pubchem: 6918289

Annotated Targets

MTOR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to temsirolimus


Feature TypeStandardized
Nominal ANOVA
mRNA SEMA6D GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA GTF2I CTRPv2 pan-cancer AAC 0.17 0.0002
mRNA CCDC117 CTRPv2 pan-cancer AAC 0.19 0.0002
mRNA SUSD4 GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA PPP2R1B GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA FRAS1 FIMM pan-cancer AAC 0.57 0.0002
mRNA MTA3 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA USP38 CTRPv2 pan-cancer AAC 0.19 0.0002
mRNA CDC123 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA TMEM45B GDSC1000 pan-cancer AAC -0.15 0.0002
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