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temsirolimus

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMTemsirolimus
CTRPv2temsirolimus
PharmacoGx temsirolimus

External IDs

DatabaseIdentifier
Smiles: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Inchikey: CBPNZQVSJQDFBE-FUXHJELOSA-N
Pubchem: 6918289

Annotated Targets

MTOR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to temsirolimus


Feature TypeStandardized
Nominal ANOVA
mRNA DTNA GDSC1000 pan-cancer AAC -0.14 3e-05
mRNA APOBEC3D GDSC1000 pan-cancer AAC 0.17 3e-05
mRNA PTPN22 GDSC1000 pan-cancer AAC 0.21 3e-05
mRNA NAA15 GDSC1000 pan-cancer AAC 0.15 3e-05
mRNA DCX GDSC1000 pan-cancer AAC -0.15 3e-05
mRNA HIBADH GDSC1000 pan-cancer AAC 0.17 3e-05
mRNA MAL2 GDSC1000 pan-cancer AAC -0.2 3e-05
mRNA FAAH GDSC1000 pan-cancer AAC -0.16 3e-05
mRNA ADAM17 GDSC1000 pan-cancer AAC 0.14 3e-05
mRNA PPFIA2 GDSC1000 pan-cancer AAC -0.14 3e-05
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