PharmacoDB

Sources

Names Used

Temsirolimus

temsirolimus

PharmacoGx

temsirolimus

Database	Identifier
Smiles:	CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Inchikey:	CBPNZQVSJQDFBE-FUXHJELOSA-N
Pubchem:	6918289

Database

Identifier

Smiles:

CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC

Inchikey:

CBPNZQVSJQDFBE-FUXHJELOSA-N

Pubchem:

Top molecular features associated with response to temsirolimus

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF646	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	ZNF652	CTRPv2	pan-cancer	AAC	0.15	0.003
mRNA	ZNF706	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	ZNF75D	FIMM	pan-cancer	AAC	0.44	0.003
mRNA	ZNF768	GDSC1000	pan-cancer	AAC	-0.094	0.004
mRNA	ZNF786	CTRPv2	pan-cancer	AAC	0.19	0.0001
mRNA	ZNRD1	CTRPv2	pan-cancer	AAC	-0.15	0.005
mRNA	ZNRF3	GDSC1000	pan-cancer	AAC	-0.13	0.0007
mRNA	ZWILCH	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	ZXDC	GDSC1000	pan-cancer	AAC	-0.11	0.001