PharmacoDB

Sources

Names Used

Temsirolimus

temsirolimus

PharmacoGx

temsirolimus

Database	Identifier
Smiles:	CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Inchikey:	CBPNZQVSJQDFBE-FUXHJELOSA-N
Pubchem:	6918289

Database

Identifier

Smiles:

CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC

Inchikey:

CBPNZQVSJQDFBE-FUXHJELOSA-N

Pubchem:

Top molecular features associated with response to temsirolimus

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FAM114A2	GDSC1000	pan-cancer	AAC	0.15	2e-05
mRNA	SLC27A2	GDSC1000	pan-cancer	AAC	-0.17	2e-05
mRNA	STYX	GDSC1000	pan-cancer	AAC	0.15	2e-05
mRNA	DECR1	GDSC1000	pan-cancer	AAC	0.15	2e-05
mRNA	RIMBP2	GDSC1000	pan-cancer	AAC	-0.17	2e-05
mRNA	ASUN	GDSC1000	pan-cancer	AAC	0.15	2e-05
mRNA	TM2D2	GDSC1000	pan-cancer	AAC	0.16	2e-05
mRNA	KLHL6	GDSC1000	pan-cancer	AAC	0.23	2e-05
mRNA	PDIK1L	GDSC1000	pan-cancer	AAC	-0.17	2e-05
mRNA	MBD2	CTRPv2	pan-cancer	AAC	0.22	2e-05