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temsirolimus

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMTemsirolimus
CTRPv2temsirolimus
PharmacoGx temsirolimus

External IDs

DatabaseIdentifier
Smiles: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Inchikey: CBPNZQVSJQDFBE-FUXHJELOSA-N
Pubchem: 6918289

Annotated Targets

MTOR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to temsirolimus


Feature TypeStandardized
Nominal ANOVA
mRNA PPM1H GDSC1000 pan-cancer AAC -0.15 2e-05
mRNA MYO1C GDSC1000 pan-cancer AAC 0.19 2e-05
mRNA SEMA3C GDSC1000 pan-cancer AAC 0.17 2e-05
mRNA ETS1 GDSC1000 pan-cancer AAC 0.16 2e-05
mRNA NFATC1 GDSC1000 pan-cancer AAC 0.17 2e-05
mRNA INSM1 GDSC1000 pan-cancer AAC -0.16 2e-05
mRNA RALGAPA2 GDSC1000 pan-cancer AAC -0.14 2e-05
mRNA SLC7A14 GDSC1000 pan-cancer AAC -0.16 2e-05
mRNA IGFBP4 GDSC1000 pan-cancer AAC 0.15 2e-05
mRNA MXI1 GDSC1000 pan-cancer AAC -0.15 2e-05
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