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temsirolimus

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMTemsirolimus
CTRPv2temsirolimus
PharmacoGx temsirolimus

External IDs

DatabaseIdentifier
Smiles: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Inchikey: CBPNZQVSJQDFBE-FUXHJELOSA-N
Pubchem: 6918289

Annotated Targets

MTOR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to temsirolimus


Feature TypeStandardized
Nominal ANOVA
mRNA FAM105A GDSC1000 pan-cancer AAC -0.16 5e-06
mRNA DPH3 GDSC1000 pan-cancer AAC 0.16 6e-06
mRNA IKZF3 GDSC1000 pan-cancer AAC 0.18 6e-06
mRNA RUNDC3B GDSC1000 pan-cancer AAC -0.16 6e-06
mRNA SAR1B GDSC1000 pan-cancer AAC 0.15 6e-06
mRNA ADCY1 GDSC1000 pan-cancer AAC -0.18 6e-06
mRNA DYRK2 GDSC1000 pan-cancer AAC -0.15 6e-06
mRNA GNG11 GDSC1000 pan-cancer AAC 0.18 6e-06
mRNA RAB17 GDSC1000 pan-cancer AAC -0.19 7e-06
mRNA DACH1 GDSC1000 pan-cancer AAC -0.16 7e-06
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