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Nilotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, FIMMNilotinib
CTRPv2nilotinib
PharmacoGx Nilotinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Pubchem: 644241

Annotated Targets

ABL1, KIT, BCR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Nilotinib


Feature TypeStandardized
Nominal ANOVA
mRNA CTNND1 CCLE pan-cancer AAC 0.25 0.0004
mRNA RPUSD3 GDSC1000 pan-cancer AAC 0.14 0.0004
mRNA ERCC2 GDSC1000 pan-cancer AAC 0.13 0.0004
mRNA ZDHHC14 CCLE pan-cancer AAC 0.17 0.0004
mRNA SPIN4 CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA RAB37 CTRPv2 pan-cancer AAC 0.14 0.0004
mRNA ZNF766 CTRPv2 pan-cancer AAC 0.14 0.0004
mRNA TRIM69 GDSC1000 pan-cancer AAC -0.14 0.0004
mRNA PHKG2 GDSC1000 pan-cancer AAC -0.13 0.0004
mRNA TTLL12 GDSC1000 pan-cancer AAC 0.13 0.0004
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