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Nilotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, FIMMNilotinib
CTRPv2nilotinib
PharmacoGx Nilotinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Pubchem: 644241

Annotated Targets

ABL1, KIT, BCR

FDA Approval Status

Approved
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Top molecular features associated with response to Nilotinib


Feature TypeStandardized
Nominal ANOVA
mRNA TOP1MT CTRPv2 pan-cancer AAC 0.25 4e-10
mRNA FAM129B GDSC1000 pan-cancer AAC 0.37 4e-10
mRNA TOM1L1 CCLE pan-cancer AAC 0.46 4e-10
mRNA MAN2A2 CTRPv2 pan-cancer AAC 0.24 5e-10
mRNA ALAS2 CCLE pan-cancer AAC 0.3 5e-10
mRNA HBA2 CTRPv2 pan-cancer AAC 0.22 5e-10
mRNA RP5-937E21.8 CTRPv2 pan-cancer AAC 0.22 5e-10
mRNA TPSG1 GDSC1000 pan-cancer AAC 0.22 6e-10
mRNA DIAPH1 GDSC1000 pan-cancer AAC 0.25 6e-10
mRNA STXBP5 CTRPv2 pan-cancer AAC 0.22 6e-10
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