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Nilotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, FIMMNilotinib
CTRPv2nilotinib
PharmacoGx Nilotinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Pubchem: 644241

Annotated Targets

ABL1, KIT, BCR

FDA Approval Status

Approved
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Top molecular features associated with response to Nilotinib


Feature TypeStandardized
Nominal ANOVA
mRNA HHEX CTRPv2 pan-cancer AAC 0.24 2e-10
mRNA ABL1 GDSC1000 pan-cancer AAC 0.24 3e-10
mRNA YPEL4 CTRPv2 pan-cancer AAC 0.22 3e-10
mRNA EEF1A1 CTRPv2 pan-cancer AAC 0.26 3e-10
mRNA HBA1 CTRPv2 pan-cancer AAC 0.22 3e-10
mRNA CRADD GDSC1000 pan-cancer AAC 0.23 3e-10
mRNA ZNF234 CCLE pan-cancer AAC 0.31 3e-10
mRNA FAM78A CTRPv2 pan-cancer AAC 0.3 3e-10
mRNA HBM CTRPv2 pan-cancer AAC 0.22 4e-10
mRNA CDT1 CTRPv2 pan-cancer AAC 0.27 4e-10
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