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Nilotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, FIMMNilotinib
CTRPv2nilotinib
PharmacoGx Nilotinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Pubchem: 644241

Annotated Targets

ABL1, KIT, BCR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Nilotinib


Feature TypeStandardized
Nominal ANOVA
mRNA RPL7A CTRPv2 pan-cancer AAC 0.28 2e-12
mRNA ALAS2 CTRPv2 pan-cancer AAC 0.25 2e-12
mRNA ICAM4 GDSC1000 pan-cancer AAC 0.26 3e-12
mRNA GCSAML GDSC1000 pan-cancer AAC 0.25 3e-12
mRNA MTO1 CTRPv2 pan-cancer AAC 0.28 4e-12
mRNA FHL3 GDSC1000 pan-cancer AAC 0.26 5e-12
mRNA GDF2 CTRPv2 pan-cancer AAC 0.24 6e-12
mRNA GATA2 GDSC1000 pan-cancer AAC 0.27 7e-12
mRNA GLUL GDSC1000 pan-cancer AAC 0.25 7e-12
mRNA WT1 GDSC1000 pan-cancer AAC 0.26 8e-12
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