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Nilotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, FIMMNilotinib
CTRPv2nilotinib
PharmacoGx Nilotinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Pubchem: 644241

Annotated Targets

ABL1, KIT, BCR

FDA Approval Status

Approved
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Top molecular features associated with response to Nilotinib


Feature TypeStandardized
Nominal ANOVA
mRNA TRDN CCLE pan-cancer AAC 0.32 4e-11
mRNA LDB1 CTRPv2 pan-cancer AAC 0.25 4e-11
mRNA EGFL7 CTRPv2 pan-cancer AAC 0.24 4e-11
mRNA OSCAR CTRPv2 pan-cancer AAC 0.24 4e-11
mRNA RFESD GDSC1000 pan-cancer AAC 0.25 4e-11
mRNA KCNH2 CTRPv2 pan-cancer AAC 0.24 4e-11
mRNA OR51B5 CTRPv2 pan-cancer AAC 0.23 4e-11
mRNA SVOPL CCLE pan-cancer AAC 0.33 5e-11
mRNA PRKCQ GDSC1000 pan-cancer AAC 0.25 5e-11
mRNA C5AR2 CTRPv2 pan-cancer AAC 0.25 5e-11
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