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Nilotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, FIMMNilotinib
CTRPv2nilotinib
PharmacoGx Nilotinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Pubchem: 644241

Annotated Targets

ABL1, KIT, BCR

FDA Approval Status

Approved
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Top molecular features associated with response to Nilotinib


Feature TypeStandardized
Nominal ANOVA
mRNA EMID1 CTRPv2 pan-cancer AAC 0.25 2e-11
mRNA IRF4 GDSC1000 pan-cancer AAC -0.32 2e-11
mRNA ENPP3 CTRPv2 pan-cancer AAC 0.24 2e-11
mRNA LCP2 GDSC1000 pan-cancer AAC 0.33 2e-11
mRNA ZNF804B CTRPv2 pan-cancer AAC 0.24 2e-11
mRNA LMO2 CTRPv2 pan-cancer AAC 0.26 2e-11
mRNA KIAA1586 CTRPv2 pan-cancer AAC 0.26 2e-11
mRNA B3GNTL1 GDSC1000 pan-cancer AAC 0.24 3e-11
mRNA HEMGN CTRPv2 pan-cancer AAC 0.24 3e-11
mRNA BMP2K CTRPv2 pan-cancer AAC 0.26 3e-11
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