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Nilotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, FIMMNilotinib
CTRPv2nilotinib
PharmacoGx Nilotinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Pubchem: 644241

Annotated Targets

ABL1, KIT, BCR

FDA Approval Status

Approved
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Top molecular features associated with response to Nilotinib


Feature TypeStandardized
Nominal ANOVA
mRNA SPTA1 CTRPv2 pan-cancer AAC 0.24 8e-12
mRNA R3HDM4 CTRPv2 pan-cancer AAC 0.26 1e-11
mRNA KIAA1586 GDSC1000 pan-cancer AAC 0.27 1e-11
mRNA ATP7B CCLE pan-cancer AAC 0.33 1e-11
mRNA GAB3 GDSC1000 pan-cancer AAC 0.3 1e-11
mRNA TRAK2 CTRPv2 pan-cancer AAC 0.27 1e-11
mRNA HPSE2 CCLE pan-cancer AAC 0.32 1e-11
mRNA TBC1D22B CTRPv2 pan-cancer AAC 0.25 1e-11
mRNA HBG2 CCLE pan-cancer AAC 0.33 1e-11
mRNA ENPP3 GDSC1000 pan-cancer AAC 0.25 1e-11
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