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Gefitinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMGefitinib
CTRPv2gefitinib
PharmacoGx Gefitinib

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
Inchikey: XGALLCVXEZPNRQ-UHFFFAOYSA-N
Pubchem: 123631

Annotated Targets

EGFR, AKT1

FDA Approval Status

Approved
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Top molecular features associated with response to Gefitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ZEB1 CTRPv2 pan-cancer AAC -0.18 4e-06
mRNA LAMA5 GDSC1000 pan-cancer AAC 0.19 5e-06
mRNA PKP1 GDSC1000 pan-cancer AAC 0.17 5e-06
mRNA FAM83H-AS1 CTRPv2 pan-cancer AAC 0.19 5e-06
mRNA C1orf74 CTRPv2 pan-cancer AAC 0.17 5e-06
mRNA SGCB GDSC1000 pan-cancer AAC -0.18 5e-06
mRNA HNF1B GDSC1000 pan-cancer AAC 0.19 5e-06
mRNA RNF149 CTRPv2 pan-cancer AAC 0.19 5e-06
mRNA FAT2 GDSC1000 pan-cancer AAC 0.19 5e-06
mRNA AKAP4 GDSC1000 pan-cancer AAC 0.14 5e-06
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