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Gefitinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMGefitinib
CTRPv2gefitinib
PharmacoGx Gefitinib

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
Inchikey: XGALLCVXEZPNRQ-UHFFFAOYSA-N
Pubchem: 123631

Annotated Targets

EGFR, AKT1

FDA Approval Status

Approved
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Top molecular features associated with response to Gefitinib


Feature TypeStandardized
Nominal ANOVA
mRNA REST FIMM pan-cancer AAC 0.43 0.009
mRNA PDDC1 GDSC1000 pan-cancer AAC -0.086 0.009
mRNA MTRR CTRPv2 pan-cancer AAC -0.094 0.009
mRNA RNASEL GDSC1000 pan-cancer AAC 0.089 0.009
mRNA HIPK3 CTRPv2 pan-cancer AAC 0.1 0.009
mRNA MET FIMM pan-cancer AAC 0.58 0.009
mRNA SPRR3 GDSC1000 pan-cancer AAC 0.088 0.009
mRNA ALDH1A2 GDSC1000 pan-cancer AAC 0.084 0.009
mRNA TAT CTRPv2 pan-cancer AAC 0.094 0.009
mRNA RPS27L GDSC1000 pan-cancer AAC -0.092 0.009
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