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Gefitinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMGefitinib
CTRPv2gefitinib
PharmacoGx Gefitinib

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
Inchikey: XGALLCVXEZPNRQ-UHFFFAOYSA-N
Pubchem: 123631

Annotated Targets

EGFR, AKT1

FDA Approval Status

Approved
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Top molecular features associated with response to Gefitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TBCB GDSC1000 pan-cancer AAC -0.089 0.008
mRNA PER3 GDSC1000 pan-cancer AAC -0.087 0.009
mRNA GPR75-ASB3 CTRPv2 pan-cancer AAC -0.1 0.009
mRNA CTSH GDSC1000 pan-cancer AAC 0.094 0.009
mRNA IL33 CTRPv2 pan-cancer AAC 0.095 0.009
mRNA GLI2 FIMM pan-cancer AAC -0.4 0.009
mRNA ZSCAN31 FIMM pan-cancer AAC 0.5 0.009
mRNA SYNGR2 GDSC1000 pan-cancer AAC 0.098 0.009
mRNA BNIPL CTRPv2 pan-cancer AAC 0.094 0.009
mRNA PKN1 GDSC1000 pan-cancer AAC -0.09 0.009
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