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Gefitinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMGefitinib
CTRPv2gefitinib
PharmacoGx Gefitinib

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
Inchikey: XGALLCVXEZPNRQ-UHFFFAOYSA-N
Pubchem: 123631

Annotated Targets

EGFR, AKT1

FDA Approval Status

Approved
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Top molecular features associated with response to Gefitinib


Feature TypeStandardized
Nominal ANOVA
mRNA EFNA1 CTRPv2 pan-cancer AAC 0.1 0.007
mRNA ZFHX4 CTRPv2 pan-cancer AAC -0.11 0.007
mRNA FSCN2 CTRPv2 pan-cancer AAC 0.1 0.007
mRNA GDI1 CTRPv2 pan-cancer AAC -0.1 0.007
mRNA C9orf85 GDSC1000 pan-cancer AAC 0.088 0.007
mRNA SPRR2F GDSC1000 pan-cancer AAC 0.087 0.007
mRNA RP4-635E18.9 CTRPv2 pan-cancer AAC -0.1 0.007
mRNA USP4 CTRPv2 pan-cancer AAC -0.11 0.007
mRNA IL36RN GDSC1000 pan-cancer AAC 0.092 0.008
mRNA ANO1 GDSC1000 pan-cancer AAC 0.11 0.008
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