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Gefitinib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMGefitinib
CTRPv2gefitinib
PharmacoGx Gefitinib

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
Inchikey: XGALLCVXEZPNRQ-UHFFFAOYSA-N
Pubchem: 123631

Annotated Targets

EGFR, AKT1

FDA Approval Status

Approved
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Top molecular features associated with response to Gefitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TYMS CTRPv2 pan-cancer AAC -0.11 0.007
mRNA RXRA CTRPv2 pan-cancer AAC 0.11 0.007
mRNA PDE7B CTRPv2 pan-cancer AAC -0.097 0.007
mRNA MBOAT1 CTRPv2 pan-cancer AAC 0.099 0.007
mRNA MRPL9 CTRPv2 pan-cancer AAC -0.1 0.007
mRNA FBXO17 CTRPv2 pan-cancer AAC -0.11 0.007
mRNA MAP1B CTRPv2 pan-cancer AAC -0.11 0.007
mRNA ZNF12 CTRPv2 pan-cancer AAC 0.099 0.007
mRNA ADAP1 CTRPv2 pan-cancer AAC 0.11 0.007
mRNA RGPD6 CTRPv2 pan-cancer AAC -0.11 0.007
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