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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA GEMIN4 CTRPv2 pan-cancer AAC 0.25 1e-11
mRNA DHX33 CTRPv2 pan-cancer AAC 0.25 4e-11
mRNA WRAP53 CTRPv2 pan-cancer AAC 0.24 4e-11
mRNA COQ3 CTRPv2 pan-cancer AAC 0.24 5e-11
mRNA NCL CTRPv2 pan-cancer AAC 0.25 6e-11
mRNA RPF2 CTRPv2 pan-cancer AAC 0.24 6e-11
mRNA SRSF7 CTRPv2 pan-cancer AAC 0.27 7e-11
mRNA NUFIP1 CTRPv2 pan-cancer AAC 0.24 7e-11
mRNA PRPF40A CTRPv2 pan-cancer AAC 0.24 8e-11
mRNA LRP1 CTRPv2 pan-cancer AAC -0.27 8e-11
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