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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA ADAM12 CTRPv2 pan-cancer AAC -0.24 6e-09
mRNA ACAP1 GDSC1000 pan-cancer AAC 0.31 7e-09
mRNA GCSH CTRPv2 pan-cancer AAC 0.21 7e-09
mRNA CDC123 CTRPv2 pan-cancer AAC 0.21 7e-09
mRNA NPM1 CTRPv2 pan-cancer AAC 0.21 7e-09
mRNA SRPK1 CTRPv2 pan-cancer AAC 0.22 8e-09
mRNA CLUH CTRPv2 pan-cancer AAC 0.21 8e-09
mRNA ILF3 CTRPv2 pan-cancer AAC 0.24 8e-09
mRNA FAM72B CTRPv2 pan-cancer AAC 0.25 8e-09
mRNA LRPPRC CTRPv2 pan-cancer AAC 0.22 9e-09
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