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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA RFC3 CTRPv2 pan-cancer AAC 0.22 4e-09
mRNA FARSB CTRPv2 pan-cancer AAC 0.22 4e-09
mRNA EIF4A1 CTRPv2 pan-cancer AAC 0.21 4e-09
mRNA SERBP1 CTRPv2 pan-cancer AAC 0.22 5e-09
mRNA LAIR1 GDSC1000 pan-cancer AAC 0.22 5e-09
mRNA CCT4 CTRPv2 pan-cancer AAC 0.21 5e-09
mRNA ATOX1 GDSC1000 pan-cancer AAC -0.19 5e-09
mRNA ZNF600 GDSC1000 pan-cancer AAC -0.18 6e-09
mRNA TYW3 CTRPv2 pan-cancer AAC 0.22 6e-09
mRNA DHX35 CTRPv2 pan-cancer AAC 0.21 6e-09
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