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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA GPR173 FIMM pan-cancer AAC -0.45 0.0004
mRNA ASNSD1 CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA DAB2 CTRPv2 pan-cancer AAC -0.15 0.0004
mRNA ZNF606 CTRPv2 pan-cancer AAC -0.13 0.0004
mRNA NAA15 CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA MYL6B GDSC1000 pan-cancer AAC 0.11 0.0004
mRNA SGTA CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA TTLL1 GDSC1000 pan-cancer AAC 0.11 0.0004
mRNA NKAIN1 GDSC1000 pan-cancer AAC 0.12 0.0004
mRNA MEGF6 CTRPv2 pan-cancer AAC -0.13 0.0004
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