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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA SYNCRIP CTRPv2 pan-cancer AAC 0.23 4e-10
mRNA SENP3-EIF4A1 CTRPv2 pan-cancer AAC 0.22 5e-10
mRNA HEATR1 CTRPv2 pan-cancer AAC 0.23 5e-10
mRNA MRPS9 CTRPv2 pan-cancer AAC 0.23 5e-10
mRNA H2AFZ CTRPv2 pan-cancer AAC 0.24 5e-10
mRNA DAB1 GDSC1000 pan-cancer AAC 0.19 6e-10
mRNA MRM3 CTRPv2 pan-cancer AAC 0.22 7e-10
mRNA RSL24D1 CTRPv2 pan-cancer AAC 0.25 7e-10
mRNA SCO1 CTRPv2 pan-cancer AAC 0.22 7e-10
mRNA IARS2 CTRPv2 pan-cancer AAC 0.24 8e-10
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