1. Home/
  2. Compounds/
  3. Methotrexate

Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA DDX20 CTRPv2 pan-cancer AAC 0.17 6e-06
mRNA RNLS GDSC1000 pan-cancer AAC -0.13 6e-06
mRNA STIM1 CTRPv2 pan-cancer AAC -0.17 6e-06
mRNA PDF CTRPv2 pan-cancer AAC 0.17 6e-06
mRNA TFAP4 CTRPv2 pan-cancer AAC 0.19 6e-06
mRNA GPR182 GDSC1000 pan-cancer AAC -0.13 6e-06
mRNA MID2 GDSC1000 pan-cancer AAC -0.15 6e-06
mRNA SLC35E1 CTRPv2 pan-cancer AAC -0.17 6e-06
mRNA ZWILCH CTRPv2 pan-cancer AAC 0.17 6e-06
mRNA RFT1 CTRPv2 pan-cancer AAC 0.17 6e-06
Download CSV