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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA YPEL3 CTRPv2 pan-cancer AAC -0.17 3e-06
mRNA AUNIP CTRPv2 pan-cancer AAC 0.18 3e-06
mRNA SPC25 CTRPv2 pan-cancer AAC 0.17 3e-06
mRNA GMPS CTRPv2 pan-cancer AAC 0.17 3e-06
mRNA MTHFD2 CTRPv2 pan-cancer AAC 0.18 3e-06
mRNA STOML1 CTRPv2 pan-cancer AAC -0.18 3e-06
mRNA RPL10A CTRPv2 pan-cancer AAC 0.21 3e-06
mRNA COX7A1 CTRPv2 pan-cancer AAC -0.17 3e-06
mRNA POLD1 CTRPv2 pan-cancer AAC 0.21 3e-06
mRNA NUP35 CTRPv2 pan-cancer AAC 0.17 3e-06
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