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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA ABHD12 CTRPv2 pan-cancer AAC -0.2 6e-07
mRNA MRPS2 CTRPv2 pan-cancer AAC 0.18 6e-07
mRNA MYO1G GDSC1000 pan-cancer AAC 0.21 6e-07
mRNA FAM98B CTRPv2 pan-cancer AAC 0.19 6e-07
mRNA MTIF2 CTRPv2 pan-cancer AAC 0.19 6e-07
mRNA SLC39A13 CTRPv2 pan-cancer AAC -0.22 6e-07
mRNA ELAVL1 CTRPv2 pan-cancer AAC 0.2 6e-07
mRNA LARS2 CTRPv2 pan-cancer AAC 0.19 6e-07
mRNA MAGED2 CTRPv2 pan-cancer AAC -0.21 6e-07
mRNA IGFBP4 CTRPv2 pan-cancer AAC -0.18 7e-07
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