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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA DTL CTRPv2 pan-cancer AAC 0.21 2e-07
mRNA PANK2 GDSC1000 pan-cancer AAC 0.15 2e-07
mRNA DDX39B CTRPv2 pan-cancer AAC 0.2 2e-07
mRNA NDC1 CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA XPO4 CTRPv2 pan-cancer AAC 0.2 2e-07
mRNA TTK CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA NUF2 CTRPv2 pan-cancer AAC 0.2 2e-07
mRNA MIS18A CTRPv2 pan-cancer AAC 0.2 2e-07
mRNA KPNA3 CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA TM4SF1 GDSC1000 pan-cancer AAC -0.2 2e-07
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