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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA MRPL30 CTRPv2 pan-cancer AAC 0.2 1e-07
mRNA CAD CTRPv2 pan-cancer AAC 0.21 1e-07
mRNA AMER2 GDSC1000 pan-cancer AAC 0.17 1e-07
mRNA CPEB4 CTRPv2 pan-cancer AAC -0.19 1e-07
mRNA HACE1 GDSC1000 pan-cancer AAC 0.16 1e-07
mRNA NOP56 CTRPv2 pan-cancer AAC 0.2 1e-07
mRNA ZNF445 GDSC1000 pan-cancer AAC 0.18 1e-07
mRNA METTL16 CTRPv2 pan-cancer AAC 0.2 1e-07
mRNA IL6ST GDSC1000 pan-cancer AAC -0.17 1e-07
mRNA RP11-159D12.5 CTRPv2 pan-cancer AAC 0.21 1e-07
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