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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA CD151 CTRPv2 pan-cancer AAC -0.24 7e-08
mRNA HNRNPA1 CTRPv2 pan-cancer AAC 0.23 7e-08
mRNA IPO5 CTRPv2 pan-cancer AAC 0.2 7e-08
mRNA UCHL5 CTRPv2 pan-cancer AAC 0.21 7e-08
mRNA GTF3C3 CTRPv2 pan-cancer AAC 0.19 8e-08
mRNA TUBE1 GDSC1000 pan-cancer AAC 0.15 8e-08
mRNA GNL3 CTRPv2 pan-cancer AAC 0.21 8e-08
mRNA ARHGAP11A CTRPv2 pan-cancer AAC 0.2 9e-08
mRNA HNRNPM CTRPv2 pan-cancer AAC 0.2 9e-08
mRNA NLE1 CTRPv2 pan-cancer AAC 0.2 9e-08
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