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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA BCL11B GDSC1000 pan-cancer AAC 0.17 4e-08
mRNA ATP6V1G2-DDX39B CTRPv2 pan-cancer AAC 0.21 4e-08
mRNA ADAT2 CTRPv2 pan-cancer AAC 0.24 5e-08
mRNA RP3-468K18.7 CTRPv2 pan-cancer AAC 0.2 5e-08
mRNA RNF11 CTRPv2 pan-cancer AAC -0.23 5e-08
mRNA VWA8 CTRPv2 pan-cancer AAC 0.21 5e-08
mRNA XRCC5 CTRPv2 pan-cancer AAC 0.21 5e-08
mRNA SAAL1 CTRPv2 pan-cancer AAC 0.2 5e-08
mRNA WDR75 CTRPv2 pan-cancer AAC 0.2 5e-08
mRNA SRSF3 CTRPv2 pan-cancer AAC 0.21 5e-08
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