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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CABP7	CTRPv2	pan-cancer	AAC	0.26	4e-07
mRNA	SQLE	CTRPv2	pan-cancer	AAC	0.26	4e-07
mRNA	PDE6B	CTRPv2	pan-cancer	AAC	0.27	4e-07
mRNA	UGT2B28	CTRPv2	pan-cancer	AAC	0.26	4e-07
mRNA	CCDC181	CTRPv2	pan-cancer	AAC	0.26	6e-07
mRNA	PDX1	CTRPv2	pan-cancer	AAC	0.28	7e-07
mRNA	B3GALT2	CTRPv2	pan-cancer	AAC	0.26	8e-07
mRNA	OLFM3	CTRPv2	pan-cancer	AAC	0.25	9e-07
mRNA	SOCS1	CTRPv2	pan-cancer	AAC	0.26	9e-07
mRNA	PCDH15	CTRPv2	pan-cancer	AAC	0.25	9e-07

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