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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SYCE2	CTRPv2	pan-cancer	AAC	0.28	2e-07
mRNA	GUCA2B	CTRPv2	pan-cancer	AAC	0.27	2e-07
mRNA	ZNF572	CTRPv2	pan-cancer	AAC	0.27	2e-07
mRNA	COL28A1	CTRPv2	pan-cancer	AAC	0.27	2e-07
mRNA	HIST1H1D	CTRPv2	pan-cancer	AAC	0.28	2e-07
mRNA	HEMK1	CTRPv2	pan-cancer	AAC	0.28	2e-07
mRNA	OR10G7	CTRPv2	pan-cancer	AAC	0.27	2e-07
mRNA	KIAA0196	CTRPv2	pan-cancer	AAC	0.26	2e-07
mRNA	GMFG	CTRPv2	pan-cancer	AAC	0.37	3e-07
mRNA	NDUFB9	CTRPv2	pan-cancer	AAC	0.26	3e-07

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