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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ATOH1	CTRPv2	pan-cancer	AAC	0.28	7e-08
mRNA	TRIB1	CTRPv2	pan-cancer	AAC	0.28	8e-08
mRNA	SYNGR4	CTRPv2	pan-cancer	AAC	0.27	9e-08
mRNA	ACAP1	CTRPv2	pan-cancer	AAC	0.36	1e-07
mRNA	TASP1	CTRPv2	pan-cancer	AAC	0.28	1e-07
mRNA	UGT2B11	CTRPv2	pan-cancer	AAC	0.27	1e-07
mRNA	SI	CTRPv2	pan-cancer	AAC	0.28	1e-07
mRNA	RGPD2	CTRPv2	pan-cancer	AAC	0.27	1e-07
mRNA	EVL	CTRPv2	pan-cancer	AAC	0.3	1e-07
mRNA	IL2RG	CTRPv2	pan-cancer	AAC	0.33	2e-07

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