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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PLCH1	CTRPv2	pan-cancer	AAC	0.32	1e-09
mRNA	GBP4	CTRPv2	pan-cancer	AAC	0.32	1e-09
mRNA	PIK3R5	CTRPv2	pan-cancer	AAC	0.34	1e-09
mRNA	GM2A	CTRPv2	pan-cancer	AAC	0.32	3e-09
mRNA	SMIM24	CTRPv2	pan-cancer	AAC	0.31	4e-09
mRNA	SMPD3	CTRPv2	pan-cancer	AAC	0.31	4e-09
mRNA	PRKCQ	CTRPv2	pan-cancer	AAC	0.32	4e-09
mRNA	HDAC4	CTRPv2	pan-cancer	AAC	0.3	5e-09
mRNA	LTB	CTRPv2	pan-cancer	AAC	0.31	7e-09
mRNA	RAG1	CTRPv2	pan-cancer	AAC	0.29	1e-08

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