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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF804B	CTRPv2	pan-cancer	AAC	0.14	0.005
mRNA	ZNF862	CTRPv2	pan-cancer	AAC	0.14	0.01
mRNA	ZNRF1	CTRPv2	pan-cancer	AAC	0.18	0.001
mRNA	ZP1	CTRPv2	pan-cancer	AAC	0.33	8e-11
mRNA	ZPR1	CTRPv2	pan-cancer	AAC	-0.18	0.001
mRNA	ZRSR1	CTRPv2	pan-cancer	AAC	0.2	0.0001
mRNA	ZSCAN20	CTRPv2	pan-cancer	AAC	0.11	0.04
mRNA	ZSCAN25	CTRPv2	pan-cancer	AAC	0.12	0.03
mRNA	ZSWIM3	CTRPv2	pan-cancer	AAC	0.12	0.03
mRNA	ZSWIM5	CTRPv2	pan-cancer	AAC	0.15	0.009

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