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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	INTS6L	CTRPv2	pan-cancer	AAC	0.13	0.04
mRNA	STARD4	CTRPv2	pan-cancer	AAC	0.11	0.04
mRNA	HR	CTRPv2	pan-cancer	AAC	0.12	0.04
mRNA	ROPN1B	CTRPv2	pan-cancer	AAC	-0.14	0.04
mRNA	C1orf194	CTRPv2	pan-cancer	AAC	0.11	0.04
mRNA	GOLGA8T	CTRPv2	pan-cancer	AAC	0.11	0.04
mRNA	HOOK3	CTRPv2	pan-cancer	AAC	0.11	0.04
mRNA	MCHR2	CTRPv2	pan-cancer	AAC	0.11	0.04
mRNA	SH2D3A	CTRPv2	pan-cancer	AAC	-0.13	0.04
mRNA	SLC8A1	CTRPv2	pan-cancer	AAC	0.11	0.04

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