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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DCP1A	CTRPv2	pan-cancer	AAC	0.19	0.001
mRNA	ZCCHC3	CTRPv2	pan-cancer	AAC	0.2	0.001
mRNA	ARL4C	CTRPv2	pan-cancer	AAC	0.2	0.001
mRNA	MYB	CTRPv2	pan-cancer	AAC	0.21	0.001
mRNA	DIP2A	CTRPv2	pan-cancer	AAC	0.17	0.001
mRNA	GLUL	CTRPv2	pan-cancer	AAC	0.17	0.001
mRNA	MEST	CTRPv2	pan-cancer	AAC	0.18	0.001
mRNA	SMAD4	CTRPv2	pan-cancer	AAC	0.19	0.001
mRNA	HBA2	CTRPv2	pan-cancer	AAC	0.17	0.001
mRNA	SLC25A43	CTRPv2	pan-cancer	AAC	-0.17	0.001

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