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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PIP4K2A	CTRPv2	pan-cancer	AAC	0.22	0.0002
mRNA	CTNNBL1	CTRPv2	pan-cancer	AAC	0.19	0.0002
mRNA	AGBL1	CTRPv2	pan-cancer	AAC	0.19	0.0002
mRNA	MAPKAPK3	CTRPv2	pan-cancer	AAC	0.2	0.0002
mRNA	ANKRD27	CTRPv2	pan-cancer	AAC	0.21	0.0002
mRNA	RAB37	CTRPv2	pan-cancer	AAC	0.21	0.0002
mRNA	POLG	CTRPv2	pan-cancer	AAC	0.21	0.0002
mRNA	CRISP2	CTRPv2	pan-cancer	AAC	0.19	0.0002
mRNA	BSDC1	CTRPv2	pan-cancer	AAC	0.2	0.0003
mRNA	ZFP36L2	CTRPv2	pan-cancer	AAC	0.2	0.0003

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