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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GPR174	CTRPv2	pan-cancer	AAC	0.2	0.0002
mRNA	DEFB112	CTRPv2	pan-cancer	AAC	0.19	0.0002
mRNA	EMID1	CTRPv2	pan-cancer	AAC	0.2	0.0002
mRNA	HPSE2	CTRPv2	pan-cancer	AAC	0.2	0.0002
mRNA	ROGDI	CTRPv2	pan-cancer	AAC	0.21	0.0002
mRNA	ADD2	CTRPv2	pan-cancer	AAC	0.21	0.0002
mRNA	CHD4	CTRPv2	pan-cancer	AAC	0.21	0.0002
mRNA	FAM117B	CTRPv2	pan-cancer	AAC	0.22	0.0002
mRNA	CBFA2T3	CTRPv2	pan-cancer	AAC	0.25	0.0002
mRNA	ARHGEF6	CTRPv2	pan-cancer	AAC	0.24	0.0002

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