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AZD1480

AZD1480

Synonyms

Sources	Names Used
CTRPv2	AZD1480
PharmacoGx	AZD1480

External IDs

Database	Identifier
Smiles:	CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem:	16659841

Annotated Targets

JAK2, JAK1, JAK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD1480

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ATP7B	CTRPv2	pan-cancer	AAC	0.2	9e-05
mRNA	ARHGAP19	CTRPv2	pan-cancer	AAC	0.25	0.0001
mRNA	PPM1L	CTRPv2	pan-cancer	AAC	0.21	0.0001
mRNA	PDE3B	CTRPv2	pan-cancer	AAC	0.22	0.0001
mRNA	FAM124B	CTRPv2	pan-cancer	AAC	0.21	0.0001
mRNA	ADAMTS20	CTRPv2	pan-cancer	AAC	0.21	0.0001
mRNA	HCG27	CTRPv2	pan-cancer	AAC	0.21	0.0001
mRNA	NKPD1	CTRPv2	pan-cancer	AAC	0.2	0.0001
mRNA	LMBR1L	CTRPv2	pan-cancer	AAC	0.21	0.0001
mRNA	MFSD2B	CTRPv2	pan-cancer	AAC	0.2	0.0001

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