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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GIMAP7	GDSC1000	pan-cancer	AAC	0.17	1e-07
mRNA	STAR	GDSC1000	pan-cancer	AAC	0.17	1e-07
mRNA	RNF157	GDSC1000	pan-cancer	AAC	-0.17	2e-07
mRNA	CBFA2T3	GDSC1000	pan-cancer	AAC	0.2	2e-07
mRNA	PARVG	GDSC1000	pan-cancer	AAC	0.2	2e-07
mRNA	IKZF3	GDSC1000	pan-cancer	AAC	-0.19	2e-07
mRNA	LILRB2	GDSC1000	pan-cancer	AAC	0.16	2e-07
mRNA	TGM5	GDSC1000	pan-cancer	AAC	0.16	2e-07
mRNA	PRAM1	GDSC1000	pan-cancer	AAC	0.17	3e-07
mRNA	SYNCRIP	GDSC1000	pan-cancer	AAC	0.16	3e-07

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