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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	LCP2	GDSC1000	pan-cancer	AAC	0.24	2e-08
mRNA	DOK2	GDSC1000	pan-cancer	AAC	0.19	2e-08
mRNA	ADGRE2	GDSC1000	pan-cancer	AAC	0.18	3e-08
mRNA	PRKCB	GDSC1000	pan-cancer	AAC	0.23	3e-08
mRNA	CLEC11A	GDSC1000	pan-cancer	AAC	0.18	5e-08
mRNA	RNASE3	GDSC1000	pan-cancer	AAC	0.17	5e-08
mRNA	CD300LF	GDSC1000	pan-cancer	AAC	0.18	5e-08
mRNA	SP140	GDSC1000	pan-cancer	AAC	-0.2	6e-08
mRNA	TIFAB	GDSC1000	pan-cancer	AAC	0.16	1e-07
mRNA	LILRA1	GDSC1000	pan-cancer	AAC	0.17	1e-07

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