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FR-180204

FR-180204

Synonyms

Sources	Names Used
GDSC1000	FR-180204
PharmacoGx	FR-180204

External IDs

Database	Identifier
Smiles:	Nc1[nH]nc2nnc(cc12)-c1c(nn2ccccc12)-c1ccccc1
Pubchem:	11493598

Annotated Targets

MAPK1, MAPK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FR-180204

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF7	GDSC1000	pan-cancer	AAC	0.098	0.004
mRNA	ZNF720	GDSC1000	pan-cancer	AAC	-0.083	0.02
mRNA	ZNF74	GDSC1000	pan-cancer	AAC	0.096	0.008
mRNA	ZNF75A	GDSC1000	pan-cancer	AAC	0.08	0.03
mRNA	ZNF765	GDSC1000	pan-cancer	AAC	0.099	0.006
mRNA	ZNF775	GDSC1000	pan-cancer	AAC	-0.079	0.04
mRNA	ZNF778	GDSC1000	pan-cancer	AAC	-0.073	0.03
mRNA	ZNF789	GDSC1000	pan-cancer	AAC	0.081	0.02
mRNA	ZNF792	GDSC1000	pan-cancer	AAC	0.076	0.03
mRNA	ZNF81	GDSC1000	pan-cancer	AAC	-0.12	0.0003

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