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Compounds
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CBB-1007
CBB-1007
Synonyms
Sources
Names Used
CTRPv2
CBB-1007
PharmacoGx
CBB-1007
Annotated Targets
KDM1A
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with CBB-1007
(per dataset)
0
50
100
150
200
250
300
350
400
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
434
Download SVG
Number of tissues tested with CBB-1007
(per dataset)
0
2
4
6
8
10
12
14
16
18
20
22
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
23
Download SVG
Dataset Select
all
CTRPv2
CBB-1007: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
0.30
COR-L88
COR-L88
PA-TU-8988S
PA-TU-8988S
SNU-1033
SNU-1033
OCI-LY-19
OCI-LY-19
HOP-92
HOP-92
EJM
EJM
OCI-LY3
OCI-LY3
HuT 78
HuT 78
NCI-H1694
NCI-H1694
NCI-H2081
NCI-H2081
OCI-LY10
OCI-LY10
Hs 934.T
Hs 934.T
MDA-MB-157
MDA-MB-157
HS578BST
HS578BST
GI-1
GI-1
IGR-1
IGR-1
KG-1-C
KG-1-C
NCI-H1651
NCI-H1651
LU-65
LU-65
A172
A172
COV644
COV644
MDA-MB-361
MDA-MB-361
NCI-H23
NCI-H23
GRANTA-519
GRANTA-519
SK-MEL-2
SK-MEL-2
HCC202
HCC202
HT-1197
HT-1197
PSTS
PSTS
Hs 822.T
Hs 822.T
Hs-578-T
Hs-578-T
RVH-421
RVH-421
TF-1
TF-1
NCI-H2196
NCI-H2196
OE21
OE21
Hs 839.T
Hs 839.T
K-562
K-562
BT286
BT286
697
697
HCC1500
HCC1500
GA-10
GA-10
OC-314
OC-314
IGR-37
IGR-37
HCT-8
HCT-8
OCI-AML3
OCI-AML3
BT179
BT179
HeLa
HeLa
DAN-G
DAN-G
U-118-MG
U-118-MG
A498
A498
IGR-39
IGR-39
SIG-M5
SIG-M5
Daudi
Daudi
SNU-C1
SNU-C1
JeKo-1
JeKo-1
Mino
Mino
MOTN-1
MOTN-1
EFM-192A
EFM-192A
KNS-62
KNS-62
BT-474
BT-474
SK-ES-1
SK-ES-1
COR-L88
PA-TU-8988S
SNU-1033
OCI-LY-19
HOP-92
EJM
OCI-LY3
HuT 78
NCI-H1694
NCI-H2081
OCI-LY10
Hs 934.T
MDA-MB-157
HS578BST
GI-1
IGR-1
KG-1-C
NCI-H1651
LU-65
A172
COV644
MDA-MB-361
NCI-H23
GRANTA-519
SK-MEL-2
HCC202
HT-1197
PSTS
Hs 822.T
Hs-578-T
RVH-421
TF-1
NCI-H2196
OE21
Hs 839.T
K-562
BT286
697
HCC1500
GA-10
OC-314
IGR-37
HCT-8
OCI-AML3
BT179
HeLa
DAN-G
U-118-MG
A498
IGR-39
SIG-M5
Daudi
SNU-C1
JeKo-1
Mino
MOTN-1
EFM-192A
KNS-62
BT-474
SK-ES-1
COR-L88: 0.29
Synonyms: COR-L88, CORL88
PA-TU-8988S: 0.25
Synonyms: PA-TU-8988S, PATU8988S
SNU-1033: 0.22
Synonyms: SNU-1033, SNU1033
OCI-LY-19: 0.21
Synonyms: OCI-LY-19, OCILY19
HOP-92: 0.19
Synonyms: HOP-92, HOP92
EJM: 0.19
Synonyms: EJM
OCI-LY3: 0.19
Synonyms: OCI-LY3, OCI-LY-3, OCILY3
HuT 78: 0.18
Synonyms: HuT 78, HuT_78, HUT78
NCI-H1694: 0.18
Synonyms: NCI-H1694, NCIH1694
NCI-H2081: 0.18
Synonyms: NCI-H2081, NCIH2081
OCI-LY10: 0.18
Synonyms: OCI-LY10, OCI-LY-10, OCILY10
Hs 934.T: 0.17
Synonyms: Hs 934.T, Hs_934.T, HS934T
MDA-MB-157: 0.17
Synonyms: MDA-MB-157, MDAMB157, mdamb157
HS578BST: 0.17
Synonyms: HS578BST
GI-1: 0.16
Synonyms: GI-1, GI1
IGR-1: 0.16
Synonyms: IGR-1, IGR1
KG-1-C: 0.16
Synonyms: KG-1-C, KG1C
NCI-H1651: 0.15
Synonyms: NCI-H1651, NCIH1651
LU-65: 0.15
Synonyms: LU-65, LU65
A172: 0.15
Synonyms: A172
COV644: 0.15
Synonyms: COV644
MDA-MB-361: 0.14
Synonyms: MDA-MB-361, MDAMB361, mdamb361
NCI-H23: 0.14
Synonyms: NCI-H23, NCIH23
GRANTA-519: 0.13
Synonyms: GRANTA-519, GRANTA519
SK-MEL-2: 0.13
Synonyms: SK-MEL-2, SKMEL2
HCC202: 0.13
Synonyms: HCC202, hcc202
HT-1197: 0.13
Synonyms: HT-1197, HT1197
PSTS: 0.12
Synonyms: PSTS
Hs 822.T: 0.12
Synonyms: Hs 822.T, Hs_822.T, HS822T
Hs-578-T: 0.12
Synonyms: Hs-578-T, Hs 578T, Hs_578T, HS578T, hs578t
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
RVH-421: 0.00
Synonyms: RVH-421, RVH421
TF-1: 0.00
Synonyms: TF-1, TF1
NCI-H2196: 0.00
Synonyms: NCI-H2196, NCIH2196
OE21: 0.00
Synonyms: OE21
Hs 839.T: 0.00
Synonyms: Hs 839.T, Hs_839.T, HS839T
K-562: 0.00
Synonyms: K-562, K562
BT286: 0.00
Synonyms: BT286
697: 0.00
Synonyms: 697
HCC1500: 0.00
Synonyms: HCC1500, hcc1500
GA-10: 0.00
Synonyms: GA-10, GA10
OC-314: 0.00
Synonyms: OC-314, OC 314, OC_314, OC314
IGR-37: 0.00
Synonyms: IGR-37, IGR37
HCT-8: 0.00
Synonyms: HCT-8, HCT8
OCI-AML3: 0.00
Synonyms: OCI-AML3, OCIAML3
BT179: 0.00
Synonyms: BT179
HeLa: 0.00
Synonyms: HeLa, HELA
DAN-G: 0.00
Synonyms: DAN-G, DANG
U-118-MG: 0.00
Synonyms: U-118-MG, U-118 MG, U-118_MG, U118MG
A498: 0.00
Synonyms: A498, A-498
IGR-39: 0.00
Synonyms: IGR-39, IGR39
SIG-M5: 0.00
Synonyms: SIG-M5, SIGM5
Daudi: 0.00
Synonyms: Daudi, DAUDI
SNU-C1: 0.00
Synonyms: SNU-C1, SNUC1
JeKo-1: 0.00
Synonyms: JeKo-1, JEKO-1, JEKO1
Mino: 0.00
Synonyms: Mino, MINO
MOTN-1: 0.00
Synonyms: MOTN-1, MOTN1
EFM-192A: 0.00
Synonyms: EFM-192A, EFM192A, efm192a
KNS-62: 0.00
Synonyms: KNS-62, KNS62
BT-474: 0.00
Synonyms: BT-474, BT474, bt474
SK-ES-1: 0.00
Synonyms: SK-ES-1, SKES1
Download SVG
5.00
10.00
15.00
20.00
25.00
30.00
35.00
40.00
45.00
50.00
55.00
60.00
EJM
EJM
GI-1
GI-1
YKG-1
YKG-1
K052
K052
DV-90
DV-90
NCI-H522
NCI-H522
SNU-475
SNU-475
KP-N-YN
KP-N-YN
OCI-LY3
OCI-LY3
JHOM-1
JHOM-1
SK-N-AS
SK-N-AS
KARPAS-422
KARPAS-422
BT-20
BT-20
Pfeiffer
Pfeiffer
BL-70
BL-70
COR-L88
COR-L88
KYSE-520
KYSE-520
SNU-16
SNU-16
M059K
M059K
GA-10
GA-10
697
697
BICR 22
BICR 22
ST486
ST486
SK-N-MC
SK-N-MC
RCC10RGB
RCC10RGB
EN
EN
DU-4475
DU-4475
EJM
GI-1
YKG-1
K052
DV-90
NCI-H522
SNU-475
KP-N-YN
OCI-LY3
JHOM-1
SK-N-AS
KARPAS-422
BT-20
Pfeiffer
BL-70
COR-L88
KYSE-520
SNU-16
M059K
GA-10
697
BICR 22
ST486
SK-N-MC
RCC10RGB
EN
DU-4475
EJM: 61.42 (log10 µM)
Synonyms: EJM
GI-1: 13.22 (log10 µM)
Synonyms: GI-1, GI1
YKG-1: 10.45 (log10 µM)
Synonyms: YKG-1, YKG1
K052: 8.70 (log10 µM)
Synonyms: K052, KO52
DV-90: 8.52 (log10 µM)
Synonyms: DV-90, DV90
NCI-H522: 5.89 (log10 µM)
Synonyms: NCI-H522, NCIH522
SNU-475: 5.30 (log10 µM)
Synonyms: SNU-475, SNU475
KP-N-YN: 5.25 (log10 µM)
Synonyms: KP-N-YN, KPNYN
OCI-LY3: 5.19 (log10 µM)
Synonyms: OCI-LY3, OCI-LY-3, OCILY3
JHOM-1: 4.83 (log10 µM)
Synonyms: JHOM-1, JHOM1
SK-N-AS: 4.73 (log10 µM)
Synonyms: SK-N-AS, SKNAS
KARPAS-422: 4.28 (log10 µM)
Synonyms: KARPAS-422, KARPAS422
BT-20: 3.64 (log10 µM)
Synonyms: BT-20, BT20, bt20
Pfeiffer: 3.10 (log10 µM)
Synonyms: Pfeiffer, PFEIFFER
BL-70: 3.08 (log10 µM)
Synonyms: BL-70, BL70
COR-L88: 2.95 (log10 µM)
Synonyms: COR-L88, CORL88
KYSE-520: 2.88 (log10 µM)
Synonyms: KYSE-520, KYSE520
SNU-16: 2.56 (log10 µM)
Synonyms: SNU-16, SNU16
M059K: 2.39 (log10 µM)
Synonyms: M059K
GA-10: 2.18 (log10 µM)
Synonyms: GA-10, GA10
697: 2.17 (log10 µM)
Synonyms: 697
BICR 22: 2.11 (log10 µM)
Synonyms: BICR 22, BICR_22, BICR22
ST486: 2.00 (log10 µM)
Synonyms: ST486
SK-N-MC: 1.99 (log10 µM)
Synonyms: SK-N-MC, SKNMC
RCC10RGB: 1.98 (log10 µM)
Synonyms: RCC10RGB
EN: 1.97 (log10 µM)
Synonyms: EN
DU-4475: 1.68 (log10 µM)
Synonyms: DU-4475, DU4475, du4475
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
CBB-1007: AAC
AAC
Tissues
0.00
0.05
0.10
0.15
0.20
0.25
0.30
cervix
cervix
upper_aerodigestive_tract
upper_aerodigestive_tract
skin
skin
oesophagus
oesophagus
prostate
prostate
unknown
unknown
ovary
ovary
large_intestine
large_intestine
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
thyroid
thyroid
liver
liver
endometrium
endometrium
pleura
pleura
central_nervous_system
central_nervous_system
bone
bone
pancreas
pancreas
breast
breast
stomach
stomach
kidney
kidney
autonomic_ganglia
autonomic_ganglia
lung
lung
urinary_tract
urinary_tract
soft_tissue
soft_tissue
0.00
1.00
2.00
3.00
4.00
5.00
6.00
7.00
8.00
9.00
10.00
11.00
12.00
13.00
large_intestine
large_intestine
pancreas
pancreas
prostate
prostate
upper_aerodigestive_tract
upper_aerodigestive_tract
oesophagus
oesophagus
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
lung
lung
ovary
ovary
unknown
unknown
thyroid
thyroid
endometrium
endometrium
stomach
stomach
breast
breast
liver
liver
central_nervous_system
central_nervous_system
skin
skin
pleura
pleura
cervix
cervix
urinary_tract
urinary_tract
soft_tissue
soft_tissue
kidney
kidney
bone
bone
autonomic_ganglia
autonomic_ganglia
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to CBB-1007
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
GZMK
CTRPv2
pan-cancer
AAC
0.18
0.0006
mRNA
ZNF527
CTRPv2
pan-cancer
AAC
0.2
0.0006
mRNA
PRSS46
CTRPv2
pan-cancer
AAC
0.18
0.0006
mRNA
LAX1
CTRPv2
pan-cancer
AAC
0.2
0.0006
mRNA
SLC26A5
CTRPv2
pan-cancer
AAC
0.18
0.0006
mRNA
ATP9A
CTRPv2
pan-cancer
AAC
0.2
0.0006
mRNA
FBXO16
CTRPv2
pan-cancer
AAC
0.18
0.0006
mRNA
ZNF260
CTRPv2
pan-cancer
AAC
0.2
0.0006
mRNA
XRN1
CTRPv2
pan-cancer
AAC
0.18
0.0006
mRNA
SDR42E2
CTRPv2
pan-cancer
AAC
0.18
0.0006
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