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alvocidib

Synonyms

SourcesNames Used
CTRPv2alvocidib
PharmacoGx alvocidib

External IDs

DatabaseIdentifier
Smiles: CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl
Pubchem: 5287969

Annotated Targets

CDK4, CDK2, CDK6, CDK1, CDK5, CDK7, CDK8, CDK9, EGFR, PYGM

FDA Approval Status

Not Approved
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Top molecular features associated with response to alvocidib


Feature TypeStandardized
Nominal ANOVA
mRNA PEA15 CTRPv2 pan-cancer AAC -0.29 1e-06
mRNA RBM10 CTRPv2 pan-cancer AAC 0.26 1e-06
mRNA VAMP5 CTRPv2 pan-cancer AAC -0.27 1e-06
mRNA NMT2 CTRPv2 pan-cancer AAC -0.25 1e-06
mRNA CD63 CTRPv2 pan-cancer AAC -0.29 1e-06
mRNA FN1 CTRPv2 pan-cancer AAC -0.25 1e-06
mRNA NRP1 CTRPv2 pan-cancer AAC -0.26 1e-06
mRNA NBR1 CTRPv2 pan-cancer AAC -0.24 1e-06
mRNA HSPB7 CTRPv2 pan-cancer AAC -0.23 2e-06
mRNA COMP CTRPv2 pan-cancer AAC -0.23 2e-06
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