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alvocidib

Synonyms

SourcesNames Used
CTRPv2alvocidib
PharmacoGx alvocidib

External IDs

DatabaseIdentifier
Smiles: CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl
Pubchem: 5287969

Annotated Targets

CDK4, CDK2, CDK6, CDK1, CDK5, CDK7, CDK8, CDK9, EGFR, PYGM

FDA Approval Status

Not Approved
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Top molecular features associated with response to alvocidib


Feature TypeStandardized
Nominal ANOVA
mRNA PLPPR1 CTRPv2 pan-cancer AAC 0.13 0.01
mRNA AKIRIN1 CTRPv2 pan-cancer AAC 0.13 0.01
mRNA IMPDH2 CTRPv2 pan-cancer AAC 0.14 0.01
mRNA BRD4 CTRPv2 pan-cancer AAC 0.13 0.01
mRNA MPHOSPH10 CTRPv2 pan-cancer AAC 0.13 0.01
mRNA DUSP14 CTRPv2 pan-cancer AAC -0.14 0.01
mRNA CHKB CTRPv2 pan-cancer AAC 0.13 0.01
mRNA LEMD2 CTRPv2 pan-cancer AAC 0.13 0.01
mRNA CUX1 CTRPv2 pan-cancer AAC -0.13 0.01
mRNA CTAG2 CTRPv2 pan-cancer AAC 0.12 0.01
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