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alvocidib

Synonyms

SourcesNames Used
CTRPv2alvocidib
PharmacoGx alvocidib

External IDs

DatabaseIdentifier
Smiles: CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl
Pubchem: 5287969

Annotated Targets

CDK4, CDK2, CDK6, CDK1, CDK5, CDK7, CDK8, CDK9, EGFR, PYGM

FDA Approval Status

Not Approved
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Top molecular features associated with response to alvocidib


Feature TypeStandardized
Nominal ANOVA
mRNA MMP2 CTRPv2 pan-cancer AAC -0.18 0.001
mRNA RPF2 CTRPv2 pan-cancer AAC 0.16 0.001
mRNA SIGMAR1 CTRPv2 pan-cancer AAC 0.16 0.001
mRNA TTLL12 CTRPv2 pan-cancer AAC 0.16 0.001
mRNA COMMD7 CTRPv2 pan-cancer AAC -0.16 0.001
mRNA RUNX3 CTRPv2 pan-cancer AAC 0.18 0.001
mRNA EXOSC2 CTRPv2 pan-cancer AAC 0.17 0.001
mRNA ZFYVE21 CTRPv2 pan-cancer AAC -0.18 0.001
mRNA SYNPO CTRPv2 pan-cancer AAC -0.18 0.001
mRNA RCN3 CTRPv2 pan-cancer AAC -0.17 0.001
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