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cediranib

cediranib

Synonyms

Sources	Names Used
CTRPv2	cediranib
PharmacoGx	cediranib

External IDs

Database	Identifier
Smiles:	COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1
Pubchem:	9933475

Annotated Targets

KIT, CSF1R, FLT1, FLT3, FLT4, KDR, PDGFRA, PDGFRB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to cediranib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MN1	CTRPv2	pan-cancer	AAC	0.15	0.005
mRNA	PLGLB1	CTRPv2	pan-cancer	AAC	0.16	0.005
mRNA	ZNF37A	CTRPv2	pan-cancer	AAC	0.17	0.005
mRNA	PPP6R2	CTRPv2	pan-cancer	AAC	0.16	0.005
mRNA	NKAIN2	CTRPv2	pan-cancer	AAC	0.15	0.005
mRNA	TMEM175	CTRPv2	pan-cancer	AAC	0.15	0.006
mRNA	APH1B	CTRPv2	pan-cancer	AAC	0.15	0.006
mRNA	LRRC8C	CTRPv2	pan-cancer	AAC	0.15	0.006
mRNA	FGL2	CTRPv2	pan-cancer	AAC	0.14	0.006
mRNA	CDCP1	CTRPv2	pan-cancer	AAC	-0.17	0.006

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