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cediranib

cediranib

Synonyms

Sources	Names Used
CTRPv2	cediranib
PharmacoGx	cediranib

External IDs

Database	Identifier
Smiles:	COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1
Pubchem:	9933475

Annotated Targets

KIT, CSF1R, FLT1, FLT3, FLT4, KDR, PDGFRA, PDGFRB

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to cediranib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FAM89B	CTRPv2	pan-cancer	AAC	0.17	0.002
mRNA	AP5B1	CTRPv2	pan-cancer	AAC	0.17	0.002
mRNA	MAPK11	CTRPv2	pan-cancer	AAC	0.16	0.002
mRNA	ARHGAP45	CTRPv2	pan-cancer	AAC	0.23	0.002
mRNA	KLHL1	CTRPv2	pan-cancer	AAC	0.16	0.002
mRNA	PRTFDC1	CTRPv2	pan-cancer	AAC	0.18	0.002
mRNA	PKIB	CTRPv2	pan-cancer	AAC	0.16	0.002
mRNA	ACAA2	CTRPv2	pan-cancer	AAC	0.17	0.002
mRNA	AKAIN1	CTRPv2	pan-cancer	AAC	0.16	0.002
mRNA	SLC34A2	CTRPv2	pan-cancer	AAC	0.16	0.002

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